Oxotremorine M iodide
CAS No. 3854-04-4
Oxotremorine M iodide ( Oxotremorine methiodide )
产品货号. M26353 CAS No. 3854-04-4
Oxotremorine M iodide is a potent and non-selective agonist of muscarinic acetylcholine receptor (mAChR).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
10MG | ¥348 | 有现货 |
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100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Oxotremorine M iodide
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Oxotremorine M iodide is a potent and non-selective agonist of muscarinic acetylcholine receptor (mAChR).
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产品描述Oxotremorine M iodide is a potent and non-selective agonist of muscarinic acetylcholine receptor (mAChR).(In Vitro):Oxotremorine M iodide robustly elicits a phosphoinositide response (EC50 = 0.22 μM).?Oxotremorine M iodide shows EC50s of 0.36, 0.52, 1.62, and 1.48 μM for wild-type, M2, M3, and M2/M3 knockout mice, respectively.?Oxotremorine M iodide (0.1-30 μM) dose-dependently inhibits KCNQ2/3 currents.(In Vivo):In male Sprague-Dawley albino rats, Oxotremorine M iodide (0.5 mg/kg; s.c.) increases DA release in the medial prefrontal cortex without affecting the nucleus accumbens.
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同义词Oxotremorine methiodide
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通路Others
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靶点Other Targets
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受体5-HT1; 5-HT2; 5-HT4
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研究领域——
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适应症——
化学信息
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CAS Number3854-04-4
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分子量322.2
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分子式C11H19IN2O
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纯度>98% (HPLC)
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溶解度——
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SMILES[I-].C[N+](C)(C)CC#CCN1CCCC1=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Marquez H, Albertí J, Salvà M, Saurina J, Sentellas S. Characterization of in vitro metabolic profiles of cinitapride obtained with liver microsomes of humans and various mammal species using UHPLC and chemometric methods for data analysis. Anal Bioanal Chem. 2012 May;403(4):909-16.
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